The miR - 282 Drosophila melanogaster microRNA gene regulates viability , longevity , and egg production

Viability, longevity, and egg production of Drosophila melanogaster are regulated by the miR-282 microRNA.

The first microRNAs were discovered some 20 years ago, but only a small fraction of the microRNA-encoding genes have been described in detail yet. Here we report the molecular analysis of a computationally predicted Drosophila melanogaster microRNA gene, mir-282. We show that the mir-282 gene is the source of a 4.9-kb-long primary transcript with a 5' cap and a 3'-poly(A) sequence and a mature ...

Structural and functional analysis of the miR-282 microRNA gene of Drosophila melanogaster Ph.D. thesis

The microRNA miR-7 regulates Tramtrack69 in a developmental switch in Drosophila follicle cells.

Development in multicellular organisms includes both small incremental changes and major switches of cell differentiation and proliferation status. During Drosophila oogenesis, the follicular epithelial cells undergo two major developmental switches that cause global changes in the cell-cycle program. One, the switch from the endoreplication cycle to a gene-amplification phase, during which spe...

Studies on natural populations of Drosophila. V. Correlated response to selection in Drosophila melanogaster.

I N the series of experiments to be described, a population of Drosophila melanogaster was selected for increase or decrease in wing length, with and without inbreeding, and the resulting changes in thorax length, rate of egg production, and longevity were observed. Heritabilities, and phenotypic and genetic correlations were also measured at intervals during the ten generations of selection. T...

Selection Against Maternal microRNA Target Sites in Maternal Transcripts

In animals, before the zygotic genome is expressed, the egg already contains gene products deposited by the mother. These maternal products are crucial during the initial steps of development. In Drosophila melanogaster, a large number of maternal products are found in the oocyte, some of which are indispensable. Many of these products are RNA molecules, such as gene transcripts and ribosomal R...